Abstract
Prolonged fluorine intake can cause skeletal fluorosis, which may affect teeth, bone tissue and secondarily the nervussislem. Growth, previous exposure to fluorides, malnutrition, inanition, acid urinary pH, enhance fluorine retention in thebody. In subacule and chronic fluorine exposure there are detectable skeletal changes (in the epiphyses of longbones,skull and cervical spine). Cost benefit ratio should be considered when fluorides are prescribed, including thehigher susceptibility of children to fluorosis, terotogenecity and the presence of mentioned risk factors. In this countryinvestigations are needed on real needs of fluorine among diferent regional communities, and appropriate knowledge onthe concenlralions of fluorine in drugs, tooth pastes, waters and foods is urged before decisions that involv e indiscriminatedfluoridalion of waters are to be taken.[Key words: fluorine, fluoridalion, fluoride poisoning, fluorides topical.!
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