Abstract

Background High permeability pulmonary edema is the basic pathophysiological characteristics of acute lung injury and acute respiratory distress syndrome (ALI/ARDS),the degree of which is directly bound up with the prognosis of ALI/ARDS. Objective Rational fluid therapy for ALI/ARDS patients can improve pulmonary edema and mortality. Content In this article,we reviewed the controversial issues,such as:① the selection of a conservative or a liberal strategy of fluid therapy,② the selection of fluid type.We also summarized the research progress in this field,such as different treatment and monitoring indicators for distinct stage in the progress of ALI/ARDS in the past few years. Trend Future research will focus on exploring specific fluid therapy strategy for ALI/ARDS during various pathophysiological stages,and seeking effective and sensitive monitoring indicators to guide the selection and adjustment of fluid therapy strategy for ALI/ARDS. Key words: Acute lung injury; Acute respiratory distress syndrome; Fluid therapy

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