Fluid therapy and hemodynamic support in septic shock

Abstract

Sepsis remains one of the leading causes of mortality in children all over the world, especially in the developing nations. Early recognition of sepsis and septic shock facilitate the resuscitation, further reducing the morbidity and mortality related to septic shock in children.Current evidence and guidelines emphasize on goal-directed therapy and institution-specific bundles in the management of septic shock in children. There is an emerging evidence for the use of newer monitoring and therapeutic modalities in the various phases of septic shock in children - especially the de-resuscitation phase, which need validation by further trials.