Abstract
The current meta-analysis found no significant difference in the mortality rate between the types of resuscitation fluid, and their speed or volume of administration. However, a significantly decreased risk of AKI was found in the BC group. More evidence is needed regarding the speed and volume of administration of fluid boluses in critically ill children.Prospero registration: CRD42020209066. • Balanced crystalloids (BC) may be better than normal saline (NS) for fluid resuscitation in critically ill children. • BC are better than NS for fluid resuscitation in critically ill children as they decrease AKI and hyperchloremia.
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