Abstract

To the Editor. — In a recent issue of Pediatrics , Healy et al1 described the continued benefit and safety of fluconazole prophylaxis in infants weighing <1000 g in preventing invasive Candida infections and eliminating these infections as a cause of mortality in their NICU. The efficacy and safety of preventing these invasive Candida infections with fluconazole prophylaxis has been proven in single and multicenter randomized trials in preterm infants without the development of resistance.2,3 In addition, retrospective studies have added safety and efficacy data from …

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