Flowable platelet rich fibrin a new trend for enhancing bone augmentation results in maxillary sinus floor augmentation. (Radiographic and histologic evaluation)

Abstract

Flowable PRF enriched and vibrant bioactivity, simplified preparation, high healing potentials and easy incorporation with other biomaterials were the key aspects to stimulate the applications of flowable PRF in various medical fields. The current study aimed to evaluate if flowable PRF has superior bone augmentation properties over the conventional PRF in sinus floor augmentation procedures. In this study 18 maxillary sinuses were augmented, which were divided into 2 groups, group A maxillary sinuses were augmented using a mixture of xenograft bone substitute, group B maxillary sinuses were augmented using a mixture of xenograft bone substitute and flowable PRF. Results: Clinically flowable PRF showed ease of preparation and improved the handling and manipulation of the bone graft particles. Radiographic results showed that Group A average gained bone height of 10.4±1.2 mms while in group B mean gained bone height was 11.6±1.9 mms, bone densities results of both groups showed that bone density units of group A were 578 ± 56 Hounsfield Units(HU), while group B calculated augmented bone densities were 586.2 ± 68 HU. Histologic evaluation stated that group I and group II revealed a lot of similarities regarding the amount and the quality of the newly formed bone. There by concluding that flowable PRF resulted in similar results to that of the conventional PRF, however the ease of preparation, application and manipulation emphasizes its benefits and recommends its application.