Abstract
Objectives: To evaluate the changes in flow mediated dilatation (FMD) and QT interval dispersion (QTd) in stable coronary artery disease (CAD) patients with or without myocardial infarction (MI). Results: 152 patients participated in the study 64 patients with MI. MI patients showed a significantly lower FMD (3.58 ± 4.45 versus 5.16 ± 4.80, p = 0.040) and higher QTd (62 ± 36 versus 56 ± 32, p = 0.036 for QTd1; 19.45 ± 11 versus 16.25 ± 10, p = 0.021 for QTd2) compared to no-MI patients. There wasn't a significant difference in FMD and QTd according to coronary artery occlusion within MI patients. In the group of no-MI patients, those with coronary occlusion showed significantly lower FMD than patients without occlusion, whereas QTd values didn't differ significantly according to the occlusion status. Conclusion: MI patients have significantly lower FMD and higher QTd compared to no-MI patients. Low FMD in no-MI patients may be an index of chronic coronary occlusion.
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