Abstract

Flow disturbance around dynamically interacting aortic junctions

Highlights

  • The preferential development of atherosclerotic lesions near arterial branches and bifurcations suggests that localizing factors such as fluid mechanical disturbances are involved in the etiology of the disease

  • The spacing between these two branches varies significantly among individuals and across species, and this spacing is expected to have a profound impact on the fluid mechanical interactions between the two branches and on the overall flow field in the abdominal aorta

  • The goal of the present study is to computationally investigate the effect of fluid mechanical interactions between the celiac and superior mesenteric arteries on the local flow field and wall shear stress distribution

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Summary

Introduction

The preferential development of atherosclerotic lesions near arterial branches and bifurcations suggests that localizing factors such as fluid mechanical disturbances are involved in the etiology of the disease. In the aorta in vivo, major branches are often in close anatomic proximity and interact fluid mechanically with one another. A prominent example where atherosclerotic lesions are prevalent is in the abdominal aorta where two major branches, the celiac and superior mesenteric arteries, emerge from the aorta along the ventral wall to form T-junctions. The spacing between these two branches varies significantly among individuals and across species, and this spacing is expected to have a profound impact on the fluid mechanical interactions between the two branches and on the overall flow field in the abdominal aorta. The goal of the present study is to computationally investigate the effect of fluid mechanical interactions between the celiac and superior mesenteric arteries on the local flow field and wall shear stress distribution

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