Abstract
In vivo dosimetry for patient radioprotection is a real challenge concerning new radiotherapy treatments. In this study we aim to develop a dosimeter based on tissue equivalent material, flexible and adaptable to the patient morphology in order to perform in vivo dosimetry for complex irradiation beams. Here, we report the evaluation in standard beams of highly flexible dosimeter composed of a silicone elastomer and containing leucomalachite green as radiochromic dye and give a first estimation of LMG-micelle hydrogel response. All results are compared to a commercially available PRESAGE® dosimeter.
Highlights
Despite the emergence of several technological innovations in the field of external radiotherapy, patient radioprotection is still a real challenge, in complex beams
We present the results of a highly flexible leucomalachite green (LMG)-based dosimeter contained in a silicone elastomer matrix and of a polymer gel made of Pluronic®, these could be mould to exactly fit the patient to obtain accurate in vivo dosimeter
The dose response of LMG elastomer is 2.2 x 10-2 Gy-1.cm-1 which is slightly higher than the value we obtained for PRESAGE® (1.6 x 10-2 Gy-1.cm-1)
Summary
Despite the emergence of several technological innovations in the field of external radiotherapy, patient radioprotection is still a real challenge, in complex beams. Radiotherapy has gained more and more complexity making failure possible at different steps of the treatment. Dosimetry and mostly in vivo dosimetry is taking a central and crucial role in quality insurance. The use of radiation sensitive matrix for dosimetry purposes was proposed as early as the 1950s [1]. New formulations [2,3,4] have been developed such as PRESAGE® [5,6,7] which contains leucomalachite green (LMG) as leucodye in a polyurethane matrix. Despite some advantages PRESAGE® presents the main drawback for our application of being a hard matrix
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