Abstract

Plasma low-density lipoprotein(LDL) oxidation substantially exacerbates atherosclerosis in type 2 diabetes(T2D). The impact of antioxidant-containing flaxseed lignan complex (FLC) consumption on LDL fatty acid conjugated diene (LDL-CD), oxidized low-density lipoprotein protein (LDLox) and total peroxyl radical-trapping antioxidant potential (TRAP) levels has never been examined in persons with T2D. It was hypothesized that FLC relative to placebo would decrease LDL-CD and LDLox via increased TRAP levels. The objective was to test this hypothesis.

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