Flawed reviews of pediatric depression studies underestimate medication effects

Abstract

The Brown University Psychopharmacology UpdateVolume 28, Issue 6 p. 1-7 Pediatric Treatment Flawed reviews of pediatric depression studies underestimate medication effects First published: 19 May 2017 https://doi.org/10.1002/pu.30234Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Abstract Previous reviews of antidepressant treatment for children and adolescents that found minimal or no positive effects failed to account for critical methodological differences in studies, a new review concludes. The author of the review, published March 3 in the American Journal of Psychiatry, states that earlier reviews have drawn questionable conclusions because they categorized many flawed pharmaceutical industry–sponsored trials that found no benefits from antidepressants as negative trials, rather than as failed trials. Accounting for this distinction leads the author of the present paper to conclude that evidence for beneficial effects of antidepressants in children and adolescents is actually strong. Volume28, Issue6June 2017Pages 1-7 RelatedInformation