Abstract
Abstract Three new flavone 6-C-glycosides, amesiflavones A–C (1-3) together with four known compounds, (+)-aptosimon (4), (+)-isolariciresinol (5), cleomiscosin A (6), and cleomiscosin C (7) were isolated from the leaves of Amesiodendron chinense (Merr.) Hu. Their structures were elucidated by spectroscopic methods, including 1D-, 2D-NMR and MS spectra and comparing with those reported in the literature. All compounds were evaluated for cytotoxic activities against five human cancer cell lines, KB, SK-LU-1, MCF-7, HepG-2, and SW-480. Compounds 1, 2, 4, 6, and 7 showed weak activity on all tested human cancer cell lines with IC50 values ranging from 71.0–146.0 μM.
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