Abstract
Fixed and flexible GnRH antagonist (GnRH-ant) protocols have been found comparable in clinical outcome and a significant reduction in GnRH-ant and gonadotropin consumption was observed with the flexible regimen. In reality, most patients on flexible regimens begin GnRH-ant on stimulation day six (S6), as in the fixed protocol. Our aim was to determine the proportion of patients stimulated on a flexible GnRH-ant regimen who met the criteria for antagonist administration after S6, and to compare their clinical characteristics and cycle outcome to patients who started the antagonist on S6 or earlier.
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