Abstract

Fixed drug eruption (FDE) usually appears as a solitary or a small number of pruritic, well circumscribed, erythematous macules that evolve into edematous plaques; these lesions typically resolve after discontinuation of the offending drug, leaving hyperpigmentation at the site of lesions. Fixed drug eruption has been mentioned previously as a disease model for elucidating the mechanism of how skin inflammation is caused by skin-resident T cells, a multistep process that results in eventual tissue damage. In this article we discuss the utility of dermoscopy as an additional tool which gives significant information aiding us to infer these complex processes seen in FDE and thus to confirm the diagnosis.

Highlights

  • Case ReportInstituto Dermatológico Dominicano y Cirugía de Piel “Dr Huberto Bogaert Díaz” C/Federico Velásquez, esq

  • Fixed drug eruption (FDE) usually appears as a solitary or a small number of pruritic, well circumscribed, erythematous macules that evolve into edematous plaques; these lesions typically resolve after discontinuation of the offending drug, leaving hyperpigmentation at the site of lesions

  • Dermoscopy is a noninvasive method that allows the in vivo evaluation of colors and microstructures of the epidermis, the dermoepidermal junction, and the papillary dermis not visible to the naked eye [8,9]

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Summary

Case Report

Instituto Dermatológico Dominicano y Cirugía de Piel “Dr Huberto Bogaert Díaz” C/Federico Velásquez, esq.

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