Five-Animal Frolics Exercise Improves Anxiety and Depression Outcomes in Patients with Coronary Heart Disease: A Single-Blind Randomized Controlled Trial.

Jun Jiang,Yuting Wang,Xue Jin,Qingbao Chi,Shui Yu

doi:10.1155/2020/6937158

Abstract

Introduction The patients with coronary heart disease (CHD) always have emotional implications. As the branch of traditional Chinese medicine, Five-Animal Frolics Exercise (FAE) is a popular mind-body exercise in China and shown to improve emotional wellbeing. Aim We aimed to explore the effects of FAE on the emotional disorders of CHD patients. Methods CHD patients were assigned into an experiment group (EG, FAE) and a control group (CG, routine nursing care). We measured serum levels of miR-124 and miR-135 and scores of the Hamilton Depression/Anxiety scale (HAMD/HAMA), Self-Rating Anxiety Scale (SAS), the Self-Rating Depression Scale (SDS), Short Form 36 Health Survey Questionnaire (SF-36), and Pittsburgh Sleep Quality Index (PSQI). Results After a 3-month FAE intervention, serum levels of miR-124 and miR-135 and the scores of HAMD/HAMA, SAS, SDS, and PSQI in the EG group were lower than those in the CG group, while SF-36 scores in the EG group were higher than those in the CG group (p < 0.05). Serum levels of miR-124 and miR-135 had a strong relationship with SAS and SDS scores (p < 0.05). Discussion/Implications for Practice. The study suggests that FAE intervention controls anxiety and depression outcomes and improves life quality in CHD patients by affecting serum levels of miR-124 and miR-135.

Highlights

As a traditional medical model shifts to a social-psychological-biological model of modern medicine, much attention is paid to the effects of psychological stress and mental disorders on coronary heart disease (CHD) [1, 2]
CHD was diagnosed according to the “Diagnostic Criteria for Coronary Atherosclerotic Heart Disease” issued by the Ministry of Health of the People’s Republic of China in 2010; the diagnostic criteria for anxiety and depression refers to the Chinese Classification of Mental Disorders (Revision 3, CCMD-3) [16]
Anxiety and depression were measured based on the Hamilton Depression Rating Scale (HAMD) and the Hamilton Anxiety Scale (HAMA). ey met the diagnostic criteria of anxiety and depression according to the HAMD, HAMA, Self-Rating Anxiety Scale (SAS), and SelfRating Depression Scale (SDS)

Summary

Introduction

As a traditional medical model shifts to a social-psychological-biological model of modern medicine, much attention is paid to the effects of psychological stress and mental disorders on coronary heart disease (CHD) [1, 2]. Psychological stress affects the neuroendocrine system and immune system, which in turn acts on the nervous system, causing anxiety and depression-like behaviors [3]. Psychological intervention has become the focus in the prevention of emotional disorders in heart disease patients [4]. Aerobic exercise can reduce the risk of adverse cardiovascular events in CHD patients and reduce the severity of anxiety and depression [5]. Exercise therapy can effectively improve anxiety, depression, and life quality. Exercise therapy can reduce the levels of various inflammatory and cardiovascular indicators, and some scholars believe that exercise therapy has a certain beneficial effect on neuroimmune [6]

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