Abstract
BackgroundDecision support tools build upon comprehensive and timely syntheses of literature. Rapid reviews may allow supporting their development by omitting certain components of traditional systematic reviews. We thus aimed to describe a rapid review approach underlying the development of decision support tools, i.e., five decision boxes (DB) for shared decision-making between seniors living with dementia, their caregivers, and healthcare providers.MethodWe included studies based on PICO questions (Participant, Intervention, Comparison, Outcome) describing each of the five specific decision. We gave priority to higher quality evidence (e.g., systematic reviews). For each DB, we first identified secondary sources of literature, namely, clinical summaries, clinical practice guidelines, and systematic reviews. After an initial extraction, we searched for primary studies in academic databases and grey literature to fill gaps in evidence. We extracted study designs, sample sizes, populations, and probabilities of benefits/harms of the health options. A single reviewer conducted the literature search and study selection. The data extracted by one reviewer was verified by a second experienced reviewer. Two reviewers assessed the quality of the evidence. We converted all probabilities into absolute risks for ease of understanding. Two to five experts validated the content of each DB. We conducted descriptive statistical analyses on the review processes and resources required.ResultsThe approach allowed screening of a limited number of references (range: 104 to 406/review). For each review, we included 15 to 26 studies, 2 to 10 health options, 11 to 62 health outcomes and we conducted 9 to 47 quality assessments. A team of ten reviewers with varying levels of expertise was supported at specific steps by an information specialist, a biostatistician, and a graphic designer. The time required to complete a rapid review varied from 7 to 31 weeks per review (mean ± SD, 19 ± 10 weeks). Data extraction required the most time (8 ± 6.8 weeks). The average estimated cost of a rapid review was C$11,646 (SD = C$10,914).ConclusionsThis approach enabled the development of clinical tools more rapidly than with a traditional systematic review. Future studies should evaluate the applicability of this approach to other teams/tools.
Highlights
Decision support tools build upon comprehensive and timely syntheses of literature
For each decision boxes (DB), we described inclusion criteria based on a PICO question (Population, Intervention, Comparison and Outcome) (Table 2) and on study design, giving priority to systematic literature reviews and, when no review was available, to randomized controlled trials (RCT)
When we found a statistically significant effect and the raw data was not available to compute absolute risks (AR) and Absolute risk difference (ARD), we mentioned that the intervention had statistically significant positive impacts, without providing any figures on the extent of this impact
Summary
Decision support tools build upon comprehensive and timely syntheses of literature. Rapid reviews may allow supporting their development by omitting certain components of traditional systematic reviews. Rapid reviews are a type of knowledge synthesis used to produce timely information to support health decisions [2]. Compared to more traditional knowledge synthesis methods, such as systematic reviews according to Cochrane [3], rapid reviews shorten or omit some of the steps from systematic reviews to achieve results in a more timely manner [2, 4, 5]. A recent study described six different methodological approaches to conducting rapid reviews [11], with content and format generally adapted to their intended use [5, 12]
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