Five resveratrol oligomers from roots of Sophora leachiana

Abstract

Five novel oligostilbenes, named leachianols C-G, were isolated from the roots of Sophora leachiana. Their structures were established by means of 2D NMR spectroscopic analysis, including HMBC, COLOC and PSNOESY, to be a resveratrol tetramer with a 2-cyclohexen-4-one ring (leachianol C), a resveratrol trimer with a dihydrobenzofuran ring (leachianol D), a regioisomer of leachianol D (leachianol E), a resveratrol dimer (leachianol F) and a stereoisomer of leachianol F (leachianol G), respectively. These oligostilbenes in S. leachiana derived from pallidol are different from those in S. moorcroftiana, which are derived from ε-viniferin.