Abstract

AbstractThe main goal in developing peptidomimetics is the stabilization of the bioactive conformation of peptides. Among all the secondary structures, turns are of paramount importance. This review highlights the recent advances in the design and synthesis of cyclic turn mimics. Both amino acids, carbo‐ and hetero‐cyclic scaffolds have been considered, focusing on their use in the preparation of peptidomimetics and on their ability to induce γ‐, β‐, and α‐turns.

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