First-trimester maternal serum screening and the risk for fetal distress during labor

Abstract

I read the article by Uccella et al.1Uccella S. Colombo G.F. Bulgheroni C.M. et al.First-trimester maternal serum screening and the risk for fetal distress during labor.Am J Obstet Gynecol. 2009; 201 (e1-6): 166Abstract Full Text Full Text PDF PubMed Scopus (23) Google Scholar The authors reported that low plasma pregnancy-associated plasma protein-A (PAPP-A) levels predicted several poor pregnancy outcomes. There seems to be a conflict between the data in the table and that in the text. The table shows a probability value for preterm delivery of less than 37 weeks as 0.22 (not significant), but the last paragraph in the Results section states that preterm delay (<37 and <34 weeks) was higher in the women with low PAPP-A levels. The same statement is also made in the Comment section (paragraph 2 on page 168).This discrepancy should be corrected. I read the article by Uccella et al.1Uccella S. Colombo G.F. Bulgheroni C.M. et al.First-trimester maternal serum screening and the risk for fetal distress during labor.Am J Obstet Gynecol. 2009; 201 (e1-6): 166Abstract Full Text Full Text PDF PubMed Scopus (23) Google Scholar The authors reported that low plasma pregnancy-associated plasma protein-A (PAPP-A) levels predicted several poor pregnancy outcomes. There seems to be a conflict between the data in the table and that in the text. The table shows a probability value for preterm delivery of less than 37 weeks as 0.22 (not significant), but the last paragraph in the Results section states that preterm delay (<37 and <34 weeks) was higher in the women with low PAPP-A levels. The same statement is also made in the Comment section (paragraph 2 on page 168). This discrepancy should be corrected. First-trimester maternal serum screening and the risk for fetal distress during laborAmerican Journal of Obstetrics & GynecologyVol. 201Issue 2PreviewThe purpose of this study was to assess whether low pregnancy-associated plasma protein-A (PAPP-A) levels in the first trimester are related to the risk of emergency cesarean section delivery (CS) for fetal distress during labor and fetal intrapartum acidemia. Full-Text PDF ReplyAmerican Journal of Obstetrics & GynecologyVol. 202Issue 5PreviewWe deeply appreciated the interest of Professor Spellacy for our article.1 Full-Text PDF