Abstract
Objective:First-time blood donors are the most common group of blood donors. They usually have different motivations for blood donation, some of which provoke the donors to hide risk factors of transfusion-transmissible infections (TTIs). Therefore, detection of TTIs among first-time donors is crucial and can decrease the rate of TTIs among blood recipients. This study aimed to evaluate the prevalence of TTIs among first-time donors in the transfusion center of Kohgiluyeh and Boyer-Ahmad Province (KBTC), Iran.Materials and Methods:This retrospective study was conducted with volunteer blood donors in 2004-2014 in the KBTC. Various data, including sex, confidential unit exclusion (CUE), previous donation history, and the laboratory findings of confirmatory tests, were extracted from blood donor software. Data were analyzed by SPSS using the chi-square test.Results:Among 198,501 blood donors, 52,527 (26.46%) were first-time donors, while 145,974 donors (73.54%) were repeat and regular donors. Most of the donors (94.5%) were male, while a minority (5.5%) were female. The CUE option was chosen by 2,237 (1.13%) donors. The incidence of hepatitis B surface antigen (HBsAg) and hepatitis C virus (HCV) was 247 (0.13%) and 134 (0.07%) among the entire study population, respectively. Three donors (0.002%) had confirmed human immunodeficiency virus (HIV), while none of the blood donors were positive for syphilis. Most of the donors with positive HBsAg (95.8%), HCV (86.6%), and HIV (100%) infection were first-time donors.Conclusion:Since TTIs are more common among first-time blood donors than regular and repeat donors, special considerations should be taken into account for this common group of blood donors.
Highlights
Blood transfusion has a fundamental role in medical services
Three donors (0.002%) had confirmed human immunodeficiency virus (HIV), while none of the blood donors were positive for syphilis
Since transmissible infections (TTIs) are more common among first-time blood donors than regular and repeat donors, special considerations should be taken into account for this common group of blood donors
Summary
Blood transfusion has a fundamental role in medical services. blood donation can improve the quality of patients’ lives, it is one of the main causes of the transmission of viral infections, including hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV). Several studies have shown that the chance of transmission of these infections is about 1% in each blood unit transfusion, while a 6.2% chance to transmit hepatitis was reported [1,2,3,4]. Since blood can only be provided by human resources, transfusion-transmissible infections (TTIs) via these products are important issues. Standard and relatively strict blood donation conditions are used by blood transfusion centers to improve blood safety. This includes a voluntary blood donation system, a confidential unit exclusion (CUE) system, the exclusion of high-risk donors, and standard and sensitive blood-borne disease detection systems. High-risk donors are those with risky behaviors, such as multiple sexual partners or intravenous drug injection, which can increase the risk of TTIs [7,8,9]
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