First Year Preliminary Results on the Use of a Monofilament Polyester Mesh With a Collagen Barrier for Primary and Incisional Ventral Hernia Repair

Abstract

Aim: The SymCHro study objective is to assess patient outcomes and surgeon satisfaction following ventral hernia repair with a three-dimensional (3D) monofilament polyester mesh (Symbotex composite mesh) that contains an absorbable collagen barrier on 1 side to minimize tissue attachment. Methods: SymCHro is a multicenter observational study of 100 consecutive patients in the French Club Hernie registry who underwent primary and incisional ventral hernia repair with a Symbotex composite mesh. The primary objective is to assess recurrences and complications within 2 years of repair. This analysis reports 1-year results from the ongoing study. Results: A total of 105 hernias (37.1% primary, 62.9% incisional) in 100 patients were repaired by open or laparoscopic surgery. The patient follow-up rate at 1 year was 94%. A total of 6 (6.0%) low-grade seromas; 3 (3.0%) cases of low-grade transitory ileus; and 1 (1.0%) recurrence, which was asymptomatic but was repaired, occurred within 1-year follow-up. No serious adverse events were reported. All surgeons responded as satisfied with mesh flexibility and ease of insertion. Relative to baseline, patient pain reduced significantly at day 1 through month 3 postoperatively. At 1 year, 88.3% (83/94) patients assessed the hernia operation results as “good” or “excellent.” Conclusion: At this 1-year analysis, 94% of patients were followed up and experienced minimal pain and low complication rates, suggesting that Symbotex composite mesh provides an effective and safe repair for primary and incisional ventral hernias.