Abstract

Abstract: The first total synthesis of the natural product iopsoralenoside, isolated from the n-butyl alcohol extract of Fructus Psoraleae (FP), was achieved in 17% yield over 7 steps. The key steps of the process were glycosylation and irradiation promoted by ultraviolet light. This synthesis provided a sufficient amount of synthesized trans- and cis-isopsoralenoside for further bioassays.

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