Abstract

AbstractThe cover picture shows buttes in the world‐famous Monument Valley. Located on the Arizona/Utah border, this place helps to pinpoint smallish Tuba City halfway down the road to Flagstaff. In 1988, members of the Anti‐Infective Division of Abbott Laboratories screened that town's soil for unknown microorganisms. Their discovery of Actinoplaces arizonaensis and its antibiotics, arizonin A1, A2, B1, B2, C1, and C3, allowed us to select arizonin C1 as a target. Our synthesis began with a Dötz benzannulation, and the stereocenters were implanted by a Sharpless dihydroxylation (>99 % ee) and an oxa‐Pictet–Spengler cyclization. Details are discussed in the article by R. Brückner et al. on p. 4765 ff. Photography credits: Wolfgang Staudt (http://www.flickr.com/photos/wolfgangstaudt/2200558634/); design credits: Dipl.‐Chem. Frank Sartorius (Universität Freiburg).

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