First results obtained in France with the latest model of the Fresenius cell separator: AS 104

Abstract

In Besançon, we carried out 40 plate-letphereses with the latest model of the Fresenius cell separator AS 104 to check this new system against the new generation of cell separators, according to the following criteria: less than 2 × 10 6 leukocytes (before filtration) and more than 5 × 10 11 platelets. The results show that platelet concentrates contained 5.04 ± 0.88 × 10 11 platelets in a total volume of 435 ± 113 mL. The mean platelet recovery was 40.95 ± 4.86% (from 31.7 to 51.6). The leukocyte content was 2.28 ± 5.48 × 10 6 and the red blood cell contamination was 3.48 ± 2.38 × 10 8. The quality of the platelets was very satisfactory. There was no problem with donor biocompatibility or procedure safety, few adverse donor reactions (0.6%) and good therapeutic efficiency of platelet concentrates.