Abstract
Kosakonia radicincitans is a species within the new genus Kosakonia. Many strains of this genus have been isolated from plants, but some strains are assumed to act as facultative human pathogens. In this study, an in-depth analysis of a Kosakonia isolate from human blood was performed. The strain was originally isolated from blood and identified as a member of the Enterobacter cloacae complex, exhibiting an atypical result in susceptibility testing. Therefore, the genetic background was examined, including phylogenetic classification and screening for virulence factors. Using whole-genome sequencing, the isolate was identified as a K. radicincitans strain, revealing a virulence gene cluster for yersiniabactin biosynthesis in contrast to all other strains of the species. Whole-genome sequencing was the perfect method for identifying putative virulence factors of a particular Kosakonia strain and will help distinguish beneficial strains from pathogenic strains in the future. To our knowledge, this is the first report of Kosakonia-related bacteraemia from Europe.
Highlights
Kosakonia radicincitans is a species within the new genus Kosakonia, until recently part of the genus Enterobacter
She was afebrile, showed atrial flutter (3:1), and a heart rate of 100/min; she was in slightly poor general condition and had pressure pain in the middle and lower abdomen. Her liver values were significantly increased. She was diagnosed with bile duct stenosis and received a stent by endoscopic retrograde cholangiopancreatography (ERCP) on the third day
One aerobic blood culture was positive for a bacterium initially identified as a member of the Enterobacter cloacae complex
Summary
Kosakonia radicincitans is a species within the new genus Kosakonia, until recently part of the genus Enterobacter. The actual number of infections could have been underestimated, as this genus is relatively new and is probably not yet included in all automated databases of bacterial diagnostic tools It seems that Kosakonia has no higher pathogenic or resistance properties than Enterobacter, making a more precise diagnosis unnecessary in many cases[4]. Description of the case: An 85-year-old woman presented at the Department of Internal Medicine, in Graz, Austria, with icterus, occasionally diffuse abdominal pain and loss of appetite Upon admission, she was afebrile, showed atrial flutter (3:1), and a heart rate of 100/min; she was in slightly poor general condition and had pressure pain in the middle and lower abdomen. Under treatment with this regime, the patient’s condition improved, and her inflammation parameters declined, and after six weeks of hospitalization, she was discharged
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
