First person – Tamio Furuse and Hiroshi Mizuma

doi:10.1242/dmm.042127

Abstract

ABSTRACTFirst Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms (DMM), helping early-career researchers promote themselves alongside their papers. Tamio Furuse and Hiroshi Mizuma are co-first authors on ‘ A new mouse model of GLUT1 deficiency syndrome exhibits abnormal sleep-wake patterns and alterations of glucose kinetics in the brain’, published in DMM. Tamio is a research and development scientist in the lab of Masaru Tamura at RIKEN BioResource Research Center, Japan, investigating the development of a new phenotyping platform of mutant mice. Hiroshi is a research scientist in the lab of Yasuyoshi Watanabe at RIKEN Center for Biosystems Dynamics Research, Japan, investigating functional brain PET imaging in mice modelling human disease.

Highlights

HM: In this study, we performed 18F-FDG PET, with the aim of understanding brain glucose kinetics in a GLUT1 deficiency syndrome (GLUT1DS) mouse model
First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms (DMM), helping early-career researchers promote themselves alongside their papers
How would you explain the main findings of your paper to non-scientific family and friends? TF: GLUT1 deficiency syndrome (GLUT1DS), an intractable form of epilepsy, is caused by dysfunction of glucose transporter 1, which delivers glucose to the brain

Summary

Introduction

HM: In this study, we performed 18F-FDG PET, with the aim of understanding brain glucose kinetics in a GLUT1DS mouse model. First person – Tamio Furuse and Hiroshi Mizuma First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms (DMM), helping early-career researchers promote themselves alongside their papers.

Results

Conclusion