First person – Sebastian Markert

doi:10.1242/bio.057760

Abstract

ABSTRACTFirst Person is a series of interviews with the first authors of a selection of papers published in Biology Open, helping early-career researchers promote themselves alongside their papers. Sebastian Markert is first author on ‘Overexpression of an ALS-associated FUS mutation in C. elegans disrupts NMJ morphology and leads to defective neuromuscular transmission’, published in BiO. Sebastian conducted the research described in this article while a PhD student in Christian Stigloher's lab at Imaging Core Facility, Biocenter, University of Wuerzburg, Germany. He is now a Postdoc in the lab of Shigeki Watanabe in Baltimore, USA, investigating how neurons communicate with each other on the molecular level.

Highlights

How would you explain the main findings of your paper to non-scientific family and friends? Muscle wasting diseases are often severe and cause premature death
First Person is a series of interviews with the first authors of a selection of papers published in Biology Open, helping early-career researchers promote themselves alongside their papers
We used light and electron microscopy to look at the nerve cells and measured their nerve signals with a tiny electrode

Summary

Introduction

How would you explain the main findings of your paper to non-scientific family and friends? Muscle wasting diseases are often severe and cause premature death. First Person is a series of interviews with the first authors of a selection of papers published in Biology Open, helping early-career researchers promote themselves alongside their papers. Sebastian Markert is first author on ‘Overexpression of an ALS-associated FUS mutation in C. elegans disrupts NMJ morphology and leads to defective neuromuscular transmission’, published in BiO. Sebastian conducted the research described in this article while a PhD student in Christian Stigloher’s lab at Imaging Core Facility, Biocenter, University of Wuerzburg, Germany.

Results

Conclusion