Abstract

ABSTRACTFirst Person is a series of interviews with the first authors of a selection of papers published in Biology Open, helping early-career researchers promote themselves alongside their papers. Ivo de Vos is first author on ‘The novel zebrafish model pretzel demonstrates a central role for SH3PXD2B in defective collagen remodelling and fibrosis in Frank-Ter Haar syndrome’, published in BiO. Ivo conducted the research described in this article while a Research Fellow in Professor Maurice van Steensel's lab at the Skin Research Institute of Singapore (SRIS), Agency for Science, Technology and Research (A*STAR), Singapore. He is now a Postgraduate House Officer in Clinical Genetics, currently working in patient care in the Department of Genetics, at the University Medical Center Groningen (UMCG), The Netherlands, investigating pathophysiological mechanisms underlying common skin conditions by studying rare genetic skin disorders, ultimately improving patient care.

Highlights

  • How would you explain the main findings of your paper to non-scientific family and friends? The Frank-Ter Haar syndrome is a rare heritable disorder

  • Ivo de Vos is first author on ‘The novel zebrafish model pretzel demonstrates a central role for SH3PXD2B in defective collagen remodelling and fibrosis in Frank-Ter Haar syndrome’, published in BiO

  • During my clinical clerkships I was intrigued by genetic skin disorders

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Summary

Introduction

How would you explain the main findings of your paper to non-scientific family and friends? The Frank-Ter Haar syndrome is a rare heritable disorder. Ivo de Vos is first author on ‘The novel zebrafish model pretzel demonstrates a central role for SH3PXD2B in defective collagen remodelling and fibrosis in Frank-Ter Haar syndrome’, published in BiO. Ivo conducted the research described in this article while a Research Fellow in Professor Maurice van Steensel’s lab at the Skin Research Institute of Singapore (SRIS), Agency for Science, Technology and Research (A*STAR), Singapore.

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