Abstract

ABSTRACTFirst Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms (DMM), helping early-career researchers promote themselves alongside their papers. Bao-Luen Chang is first author on ‘Semiology, clustering, periodicity and natural history of seizures in an experimental occipital epilepsy model’, published in DMM. Bao-Luen conducted the research described in this article while a PhD student in Professor Stephanie Schorge's lab at Department of Clinical and Experimental Epilepsy, UCL Queen Square Institute of Neurology (IoN), Queen Square, London, WC1N 3BG, UK. He is now a neurologist consultant and physician scientist in the lab of Professor Stephanie Schorge at No.5, Fuxing St., Guishan District, Taoyuan City 333, Taiwan, investigating mechanisms of epileptogenesis, epilepsy and pathophysiology of pharmacoresistant epilepsy.

Highlights

  • First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms (DMM), helping early-career researchers promote themselves alongside their papers

  • Most models of epilepsy in research represent a different type of epilepsy that arises from a part of the brain that can be removed, and there is little known about how to treat the patients with focal neocortical epilepsy, and few studies looking at how this epilepsy may be different from the epilepsies that are currently treated by resection

  • We have shown that this model can be a valuable tool for studying the causes of epilepsy as well as for preclinical evaluation of new strategies to treat epilepsy

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Summary

Introduction

First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms (DMM), helping early-career researchers promote themselves alongside their papers. Bao-Luen Chang is first author on ‘Semiology, clustering, periodicity and natural history of seizures in an experimental occipital epilepsy model’, published in DMM.

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