Abstract
Introduction. HAIs present a major public health problem with an impact on morbidity, mortality and quality of life. The objective of the study was to highlight the problem of HAIs and AM use, identification of risk factors and raising awareness of the phenomenon.
 Material and methods. The methodology of the PPS was patient-based, developed based on ECDC Protocol 5.3/2016. The study was accomplished in 2018. The sample of the PPS included 67 hospitals, 546 wards and 10594 patients.
 Results. The prevalence of HAIs was 1,6%, with predominance of pneumonia (25%), SSI (16.1%), LRI (14.9%), UTI (11.3%) and varies depending on the wards profile, clinical diagnosis, length of hospital stay and risk factors (medical device, surgery). HAIs were caused by Klebsiella spp. in 26%, Enterococcus spp. – 18% and coagulase-negative Staphylococci – 14%, P. aeruginosa – 12%. Klebsiella spp. presented resistance to 3rd generation cephalosporins in 84,6% and to carbapenems – 46.2%. The prevalence of AM use was 42.7%, for the group of 3rd generation cephalosporins – 34.5%. More frequently antibiotics were administered for treatment (73.8%), and for surgical prophylaxis >1 day in 93.5%.
 Conclusions. Data on HAIs and AM consumption in hospitals, first obtained by implementing active surveillance based on the ECDC tool, are standardized and comparable at national and international level and allow assessing the situation in hospitals, obtaining evidence for infection prevention and control and AM stewardship programmes at local level, as well as reasoning the national policies.
Highlights
FIRST NATIONAL POINT PREVALENCE SURVEY OF HEALTHCARE-ASSOCIATED INFECTIONS AND ANTIMICROBIAL USE IN ACUTE CARE HOSPITALS IN THE REPUBLIC OF MOLDOVA Introduction
HAIs were caused by Klebsiella spp. in 26%, Enterococcus spp. – 18% and coagulase-negative Staphylococci – 14%, P. aeruginosa – 12%
More frequently antibiotics were administered for treatment (73.8%), and for surgical prophylaxis >1 day in 93.5%
Summary
Metodologia studiului de prevalență de moment a infecțiilor asociate asistenței medicale și consumului antimicrobienelor în spitale (PPS) a fost elaborată în baza Protocolului 5.3/2016 dezvoltat de Centrul European de Prevenire și Control al Bolilor (ECDC) [9], bazată pe pacient, incluzând prevenirea și controlul IAAM și principalele variabile din ESAC (European Surveillance of Antimicrobial Consumption Network). Durata medie de spitalizare a pacienților o constituie 9,5 zile, variind de la 1,1 zile până la 64,2 zile per spital. Numărul mediu de asistenți medicali în secțiile ATI/Reanimare/STROKE pentru un pat constituie 1,7 și variază de la 0,4 până la 4,0. Numărul mediu al infirmierilor în secțiile ATI/Reanimare/STROKE pentru un pat constituie 0,9 cu variabile minime de 0,25 și maxime – de 1,8. Prezența paturilor dotate cu dozatoare pentru antiseptic (AHR) au raportat 40,3% dintre spitale, rata medie a paturilor dotate cu astfel de dispozitive fiind de 5,1%. În funcție de specialitatea secției rata paturilor dotate cu dozatoare AHR variază de la zero în secțiile cu profil psihiatrie și reabilitare până la 47,6% în secțiile ATI/Reanimare/STROKE (fig.). Rata lucrătorilor medicali care dispun de dozatoare portabile cu antiseptic pentru igiena mâinilor variază de la spital la spital.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
