First manic episode during COVID-19 infection after IVF treatment: A case report.

Abstract

Although the COVID-19 infection had mostly caused respiratory system symptoms, some patients have also been presenting with neurological and psychiatric symptoms during the pandemic the world is currently in. It is suggested that COVID-19 infection causes these symptoms by affecting the central nervous system and by also creating disadvantageous psychosocial factors for patients. Although few, cases of mania and psychosis associated with COVID-19 infection have been reported in the literature. In this case, we present a female patient who experienced their first manic episode during a COVID-19 infection, with which she was infected after an incidental IVF treatment. The 40-year-old female patient was brought to the emergency department with symptoms of sleep impairment, abnormal and disorganized motor behavior, sudden increase in energy levels, logorrhea, loose associations, and pressured speech. After the first evaluation, the patient was admitted to the psychiatry department and started up on 5 milligrams of Haloperidol. During follow-ups, the treatment doses were gradually increased to 20 milligrams of Haloperidol a day. On the 14th day of hospitalization, the patient's Young Mania Rating Scale had regressed respectively, and the patient was discharged for later outpatient follow-up. This case caught our attention for its relevance to the relation between COVID-19 and neuropsychiatric symptoms. While our case report supports the previous literature on this subject, we think that more extensive studies are needed for understanding the neuropsychiatric effects of COVID-19 infection on female patients of reproductive age.