Abstract

Biliary tract cancers have the second highest primary liver tumour incidence after hepatocellular carcinoma.1 They are classified into three subtypes (intrahepatic cholangiocarcinoma, extrahepatic cholangiocarcinoma, and gallbladder carcinoma) on the basis of anatomical location, with specific epidemiological, molecular, and therapeutic features.1 The incidence of intrahepatic cholangiocarcinoma is increasing, particularly in high-income countries, in relation to improvement in the differential diagnosis of hepatocellular carcinoma and liver metastases from other adenocarcinomas, and the rising rates of obesity, diabetes, and alcohol use.

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