First identification of mammalian orthoreovirus type 3 in diarrheic pigs in Europe.

Davide Lelli,Maria Serena Beato,Laura Baioni,Stefania Leopardi,Chiara Chiapponi,Antonio Lavazza,Lara Cavicchio,Ana Moreno,Paola De Benedictis

doi:10.1186/s12985-016-0593-4

Abstract

Mammalian Orthoreoviruses 3 (MRV3) have been described in diarrheic pigs from USA and Asia. We firstly detected MRV3 in Europe (Italy) in piglets showing severe diarrhea associated with Porcine Epidemic Diarrhea. The virus was phylogenetically related to European reoviruses of human and bat origin and to US and Chinese pig MRV3.

Highlights

The Reoviridae family consists of two subfamilies: Spinareovirinae and Sedoreovirinae, including 9 and 6 genera, respectively
The species Mammalian orthoreovirus (MRV) has been divided into three serotypes according to the capacity of type-specific antisera to neutralize virus infectivity and inhibit hemagglutination, with the prototype isolates being type 1 Lang (T1L), type 2 Jones (T2J), type 3 Dearing (T3D) and Abney (T3A)
Mammalian Orthoreoviruses 3 (MRV3) has been recently isolated from piglets with severe diarrhea and respiratory symptoms in China, Korea and the US, in association with coronaviruses of Porcine Epidemic Diarrhea (PEDV) and Transmissible Gastroenteritis (TGEV), and with Porcine A-C rotaviruses (GARVs, GCRVs) [6–8]

Summary

Introduction

The Reoviridae family consists of two subfamilies: Spinareovirinae and Sedoreovirinae, including 9 and 6 genera, respectively. MRV3 has been recently isolated from piglets with severe diarrhea and respiratory symptoms in China, Korea and the US, in association with coronaviruses of Porcine Epidemic Diarrhea (PEDV) and Transmissible Gastroenteritis (TGEV), and with Porcine A-C rotaviruses (GARVs, GCRVs) [6–8]. We here report the first isolation and characterization of MRV3 from swine fecal samples in Europe.

Results

Conclusion