Abstract
ABSTRACTPregabalin is a novel isomer of gamma-aminobutyric acid that functions as a major inhibitory neurotransmitter in the brain. It is used daily in medical practice for treating neuropathic pai...
Highlights
Pregabalin is a novel isomer of gamma-aminobutyric acid that functions as a major inhibitory neurotransmitter in the brain
There is no information in the literature that addresses whether the rapid discontinuation of pregabalin can cause psychosis to occur
Studies have shown that the abrupt discontinuation of pregabalin may lead to withdrawal symptoms that are suggestive of physical dependence, such as insomnia, nausea, headache, and diarrhoea [6]
Summary
Pregabalin is a novel isomer of gamma-aminobutyric acid (GABA) that functions as a major inhibitory neurotransmitter in the brain. The patient exhibited signs of withdrawal that included paranoid ideation, auditory hallucinations, and mutism He had engaged in self-mutilative actions and had attempted suicide. The patient was assessed according to the Diagnostic and Statistical Manual (DSM-5); he received a SAPS score of 47 and a SANS score of 59 As a result, he was diagnosed with his first psychotic episode. Seven days after beginning treatment with olanzapine, the patient’s complaints began to diminish At that time, he was reassessed according to the DSM-5; he received a SAPS score of 36 and a SANS score of 45. On the 20th day, the patient’s complaints had largely declined He was assessed according to the DSM-5 and received SAPS and SANS scores of 15 and 18, respectively. After treating with olanzapine for six months, the patient reported that he had no further psychiatric complaints
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
