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Abstract
Drug reaction with eosinophilia and systemic symptoms (DRESS) is a hypersensitivity reaction that is usually drug induced. The acronym VRESS (V for viral)1 was proposed in cases of proven viral reactivations. We describe a case that was unrelated to any drug or viral reactivation, but was triggered by a spider bite instead. Spider bites have been recently reported to cause acute generalized exanthematous pustulosis (AGEP) and other cutaneous reactions, but not DRESS.
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