Abstract
TiCl4 and ZnCl2 supported on silica gel catalyze the reactions of furan with methyl, (1R,2S,5R)-menthyl, and (1R,2S,5R)-8-phenylmenthyl acrylates. The best results are obtained when reactions are carried out without a solvent. The endo/exo and diastereofacial selectivities depend on the nature of the catalyst and on the reaction conditions. With the (1R,2S,5R)-menthyl acrylate 44% de in endo cycloadducts and 20% de in exo cycloadducts are the best asymmetric inductions. With the (1R,2S,5R)-8-phenylmenthyl acrylate 68% de in endo and 70% de in exo cycloadducts are obtained.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.