Abstract

Kinship testing and identification of human remains in forensic and anthropological fields is commonly based on the analysis of short tandem repeats (STRs) or more seldom single nucleotide polymorphisms (SNPs). In this study, another type of genetic variations, insertion/deletion polymorphisms (indels) was used through the DIPplex indels typing kit (Qiagen) for such purpose. The objective was to evaluate the performance of the assay for the analysis of ancient DNA samples as well as the informativeness of the kit on kinship investigation. Although some limitations have been noticed, this work shows that indels are well suited for the analysis of degraded samples and that they might be an interesting strategy in addition to STRs typing.

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