FIRE: A compact nanodosimeter detector based on ion amplification in gas

Abstract

One goal of nanodosimetry is to determine statistical quantities of ionization distributions in nanometric volumes. It is hypothesized here that these quantities are related to the initial biological damages in DNA from ionizations. Thus nanodosimetric quantities will potentially complement or replace the concept of RBE-weighted absorbed dose and hence they could be applied in treatment planning systems, risk assessments for radiation protection and space radiation. The development of a compact and portable nanodosimeter detector available for clinical routine is a significant step towards that goal. We present extensive measurements to characterize the performance of the FIRE (Frequency of Ion REgistration) nanodosimeter detector. It operates on similar principles like the Gas Electron Multiplier (GEM). Contrary to GEMs the FIRE detector registers positive ions instead of electrons and operates at low pressures of 0.5 Torr to 2.5 Torr. In addition, the FIRE nanodosimeter capitalizes on the usage of a resistive cathode in order to suppress discharges. Moreover, the geometry of the FIRE detector is adapted to the low pressure by enlarging the typical dimensions of a GEM foil by two orders of magnitude.The authors present two configurations of the compact FIRE nanodosimetry detector. The resistivities of the two configurations differ by six orders of magnitude. The lower resistivity should allow for faster removal of the charges attached to the wall inside the hole channel. Measurements of mean number of ions produced by 5MeV alpha particles in low pressure propane gas, mean number of dark counts, the ion arrival time, and the mean avalanche charge are presented. The dependency of these parameters on acceleration voltage, drift voltage, pressure and hole diameter were investigated.