Fipronil and its transformation products in the Yangtze River: Assessment for ecological risk and human exposure

Abstract

Fipronil (FP), a phenylpyrazole insecticide, is widely used in agricultural, residential, and veterinary settings. It is toxic to ecosystems and humans; moreover, some of its transformation products are more toxic than FP. A comprehensive profile of the contamination of the Yangtze River by FP and its transformation products (FPs) is not yet available. This study aims to fill this data gap. A total of 144 water samples were collected from 72 sampling locations along the river during the wet (June 2021) and dry (December 2020) seasons. High detection rates (85.4–91.7%) of FPs were found, with ΣFPs' median concentration of 0.49 ng/L. The parent compound FP was the most abundant (median: 0.13 ng/L), followed by FP-desulfinyl (0.08), FP-sulfone (0.07), FP-detrifluoromethylsulfinyl (DTF, 0.07), FP-sulfide (0.06) and FP-amide (0.06). Their concentrations increased significantly from the upper to the lower reaches; for approximately every 100 km toward the lower reaches, the level of FPs increased by 13–15%. The urban region and wet season had the higher FPs contamination. Through water ingestion, the human exposure risk posed by FPs in the river was acceptable; however, the ecological risk assessment showed a moderate to high risk posed by FPs. Follow-up studies are warranted to establish integrated ecological risk assessment models and conduct epidemiological risk assessments among population groups with high exposure levels of FPs. Given the high ecological risk of FPs, regular monitoring of them in the Yangtze River is necessary. FP-DTF was reported in surface water for the first time.