Abstract
We identified the first two cases of the Finnish new variant of Chlamydia trachomatis (F-nvCT) beyond Finland in two clinical urogenital specimens in Örebro County, Sweden. These Aptima Combo 2 assay-negative specimens were Aptima Chlamydia trachomatis (CT) assay positive and had the characteristic C1515T mutation in the 23S rRNA gene. From 22 March to 31 May 2019, 1.3% (2/158) of the CT-positive cases in Örebro County were missed because of the F-nvCT. International awareness, investigations and actions are essential.
Highlights
Citation style for this article: Unemo Magnus, Hansen Marit, Hadad Ronza, Lindroth Ylva, Fredlund Hans, Puolakkainen Mirja, Sundqvist Martin
We identified the first two cases of the Finnish new variant of Chlamydia trachomatis (F-nvCT) beyond Finland in two clinical urogenital specimens in Örebro County, Sweden
We identified the first two cases of F-nvCT beyond Finland, in two clinical specimens in Örebro County, Sweden
Summary
Citation style for this article: Unemo Magnus, Hansen Marit, Hadad Ronza, Lindroth Ylva, Fredlund Hans, Puolakkainen Mirja, Sundqvist Martin. Finnish new variant of Chlamydia trachomatis escaping detection in the Aptima Combo 2 assay present in Örebro County, Sweden, May 2019. We identified the first two cases of the Finnish new variant of Chlamydia trachomatis (F-nvCT) beyond Finland in two clinical urogenital specimens in Örebro County, Sweden. These Aptima Combo 2 assay-negative specimens were Aptima Chlamydia trachomatis (CT) assay positive and had the characteristic C1515T mutation in the 23S rRNA gene. Gonorrhoeae negative) from 22 March 2019 to 31 May 2019 in Örebro County, Sweden; and (iv) partial 23S rRNA gene by sequencing (personal communication, K Hokynar, May 2019) in AC2 CT-negative/equivocal specimens that were ACT positive
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