Finite Element Simulation: The Effects of Loading Modes at Different Anatomical Sites of Trabecular Bone on Morphological Indices

Abstract

The relationship between morphological parameter and different type of loading orientation on elastic behavior and yielding of trabecular may provide insight towards osteoporotic bone losses during normal activities. This paper attempts to predict the elastic and failure behavior of different loading modes (tensile and compression) on anatomic sites and morphological indices through finite element (FE) simulation. Specimens extracted from bovine femoral trabecular bone were imaged using micro computed tomography (μCT). Morphological studies were done followed by FE analysis. Results demonstrated differences between yield behaviors on anatomic sites were reflected onto the morphological indices and the type of loading modes. The yield initiated earlier in rod-like than plate-like trabecular in both loading condition but showed different failure behavior in rod-like trabecular with small differences in maximum stress between tensile and compressive. However, in many cases, trabecular models tend to have oblique fracture pattern in all anatomic sites. Through these findings, improved prediction of elastic properties and yield behavior by computational means provide insight in the development of bone substitute material depending on the anatomic site as well as in osteoporotic bone pathological treatment to monitor losses in trabecular struts.