Abstract

Arterial diseases, promoted by modification of arterial wall properties, are among the main causes of morbidity and mortality. Biomechanical parameters, including mechanical wall stress, are important factors determining arterial function in normal and pathological conditions. This investigation aims to determine dynamic stress distribution in the arterial wall 7subjected to physiological pressure waveforms. Finite element models of a typical artery were developed to evaluate Von Mises stress in the arterial wall due to physiological pressure waveforms and with differing mechanical parameters, including Young’s modulus of elasticity, non-linear stress-strain relationship and visco-elastic parameter, and appropriate boundary conditions allowing radial expansion. Results showed marked effects by mentioned parameters on maximum, minimum and amplitude of the stress wave and stress waveform. This study suggest to analyse fatigue effects of the arterial wall due to differing stress waveforms and values.

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