Fine Needle Aspiration Biopsy Mempunyai Peranan Penting dan Akurasi Tinggi Sebagai Metode Diagnostik Preoperatif Tumor Tulang

Abstract

ABSTRACT Fine Needle Aspiration Biopsy (FNAB) technique is gaining increasing popularity in the diagnosis of musculoskeletal lesions because it offers some advantages such as rapid , easy , with minimal complications, but its applicability in diagnosis of bone tumors however has some limitations. This research was aimed to explore the roles of FNAB and its accuracy as the preoperative diagnostic method compared to histopathology examination from open biopsy or operation as a gold standard. Research design was descriptive study and diagnostic test from cases of bone tumors which were aspirated over a period of three years in Anatomic Pathology Laboratory of Saiful Anwar Hospital Malang. The data was collected with cross sectional method. Of the 106 patients who were subjected to FNAB, 22 cases were diagnosed as benign bone tumor,49 were primary malignant bone tumor,24 were metastatic malignant bone tumor,1 cases was suspicious malignant tumor, 5 cases were non neoplastic lesions, and 5 cases were inadequate/ inconclusive for diagnosis. Of the 16 cases which was analized with diagnostic test, sensitivity of FNAB as preoperative diagnostic method was 100 %, specificity was 90,91%, positive predictive value was 83,33 % and negative predictive values was 100 % . Overall, diagnostic accuracy of FNAB was 93,75 %.It can be concluded that