Abstract

It is quite remarkable that pathological state of living soft tissue highly correlates with quasi-static mechanical properties, i.e., particularly elasticity. With such a fact in mind, we previously developed the iterative 2D rf-echo phase matching that determines 2D displacement vector field generated in in vivo soft tissue during acquisition of two successive rf-echo data frames. That is, since this displacement measurement allows an accurate estimate of resultant strain distributions to be obtained, we can stably quantify tissue elasticity by determining relative shear modulus distribution. Toward finer elasticity imaging, we recently improved previous displacement measurement method such that better phase matching can be realized. That is, we novelly incorporate an effective mechanism into previous one: local region size is made suitably smaller during iterative phase matching. This leads to improvement of quality of finally obtained elasticity image. The effectiveness was verified through simulation, and an experiment on in vitro pork and in vivo breast tissues.

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