Finding key impurities in different manufacturing routes of a drug substance using liquid chromatography/mass spectrometry followed by principal components analysis

Abstract

Rapid Communications in Mass SpectrometryVolume 21, Issue 23 p. 3946-3948 Letter to the Editor Finding key impurities in different manufacturing routes of a drug substance using liquid chromatography/mass spectrometry followed by principal components analysis Dan Carrier, Corresponding Author Dan Carrier dan.j.carrier@gsk.com GlaxoSmithKline, Gunnels Wood Road, Stevenage SG1 2NY, UKGlaxoSmithKline Research, Gunnels Wood Road, Stevenage SG1 2NY, UK.Search for more papers by this authorChristine Eckers, Christine Eckers GlaxoSmithKline, Gunnels Wood Road, Stevenage SG1 2NY, UKSearch for more papers by this authorTiffanie Arnoult, Tiffanie Arnoult GlaxoSmithKline, Gunnels Wood Road, Stevenage SG1 2NY, UKSearch for more papers by this authorThomas Thurston, Thomas Thurston GlaxoSmithKline, Old Powder Mills, Tonbridge TN11 9AN, UKSearch for more papers by this authorHilary Major, Hilary Major Waters, Atlas Park, Simonsway, Manchester M22 5PP, UKSearch for more papers by this author Dan Carrier, Corresponding Author Dan Carrier dan.j.carrier@gsk.com GlaxoSmithKline, Gunnels Wood Road, Stevenage SG1 2NY, UKGlaxoSmithKline Research, Gunnels Wood Road, Stevenage SG1 2NY, UK.Search for more papers by this authorChristine Eckers, Christine Eckers GlaxoSmithKline, Gunnels Wood Road, Stevenage SG1 2NY, UKSearch for more papers by this authorTiffanie Arnoult, Tiffanie Arnoult GlaxoSmithKline, Gunnels Wood Road, Stevenage SG1 2NY, UKSearch for more papers by this authorThomas Thurston, Thomas Thurston GlaxoSmithKline, Old Powder Mills, Tonbridge TN11 9AN, UKSearch for more papers by this authorHilary Major, Hilary Major Waters, Atlas Park, Simonsway, Manchester M22 5PP, UKSearch for more papers by this author First published: 27 November 2007 https://doi.org/10.1002/rcm.3284Citations: 5Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Citing Literature Volume21, Issue2315 December 2007Pages 3946-3948 RelatedInformation