Final observation of an extremely severe case of Osler-Weber-Rendu disease in teaching at the pregraduate and postgraduate stages of education and the use of current English-language Internet applications for doctors and patients

Abstract

Hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu syndrome, Osler-Weber-Rendu disease, etc) is diagnosed clinically according to the so called Curacao criteria, if at least three of four of them are present: recurrent spontaneous epistaxis, mucocutaneous telangiectasias on characteristic locations, visceral vascular lesions and same disease in close relative. The described clinical case with dramatic outcome demonstrates an extremely severe course of Osler-Weber-Rendu disease complicated with recurrent massive epistaxis, long severe posthemorrhagic anemia requiring systemic red blood cell transfusions all of which became unfavorable background for the development of a fatal coronavirus disease. Demonstrations to students and interns of a rare clinical case of hereditary hemorrhagic telangiectasia with the use of actual English-language Internet sites help to improve the process of teaching general practice — family medicine at the pregraduate and postgraduate levels.