Abstract
Film forming gels are a novel approach in this area that might present at an alternative to the conventional dosage form used on the skin , such as ointments , creams , gels or patches. The polymeric solution is applied to the skin as a liquid and forms an alomost invisible film in situ by solvent evaporation. transdermal drug delivery system and dermal drug delivery system can provide some desirable performance over conventional pharmaceutical dosage formulations, such as avoiding gut and hepatic first-pass metabolism, improving drug bioavailability, reducing dose frequency and stabilizing drug delivery profile. The aim of this review was to search for alternative to conventional forms in order to reduce skin irritation, improve skin adhesion properties, enhance the drug release and increase the patient acceptability from an aesthetic perspective. Because of their peculiar rheological behavior, polymeric gels are beneficial in terms of ease of preparation, ease of application, adhesion to the application surface and ability to deliver a wide variety of drugs.
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