Abstract
Blood samples from 96 subjects from 5 villages in an area endemic for Malayan filariasis in Malaysia were examined for the presence of microfilariae, level of eosinophilia, and presence of antibodies to microfilariae and to infective larvae of Brugia malayi. Subjects were grouped according to clinical signs or symptoms attributable either to readily discernible filarial infections or to a form of occult filariasis generally known as “eosinophilic lung”. Certain patterns of antibody production were discernible in that humoral antimicrofilarial antibodies were found in all persons with elephantiasis and in smaller proportions of subjects in other groups, but not in subjects with microfilaraemia or chronic asthma. Antibodies against the infective larva were commonly found in all groups, most often in subjects with microfilaraemia, elephantiasis, and eosinophilia. The interrelationships between sensitization to filarial antigens in subjects with microfilaraemia, eosinophilia, and occult filariasis were discussed.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Transactions of the Royal Society of Tropical Medicine and Hygiene
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
