Abstract
Over a 10-month period we observed 6 cases of human alveolar cell carcinoma, a relatively uncommon human tumor. Electron microscopy study of freshly excised tumor tissue revealed intracytoplasmic vacuoles with dense osmophilic inclusions containing filaments in 4 cases. The filamentous structures were about 90 nm in diameter, with a central core about 15 nm in diameter. Spherical bodies about 90–130 nm in diameter in the vacuolar space had a double membrane, and electrondense particles randomly dispersed in their matrices.
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