FIGURE 4 from The Cross-talk Between Intestinal Microbiota and MDSCs Fuels Colitis-associated Cancer Development

Atara Uzan-Yulzari,Carmel Even,Eli Pikarsky,Hadas Ashkenazi-Preiser,Ivan Mikula,Kerem Ben-Meir,Leonor Cohen-Daniel,Michal Baniyash,Nira Twaik,Omry Koren,Or Reuven,Roy Cirkin,Sharon Komisarov,Sondra Turjeman,Yaron Meirow,Yoram Louzoun

doi:10.1158/2767-9764.25605614

Abstract

Initial microbiota composition correlates with tumor load and predicts tumor development. A, Taxonomy tree of bacteria correlated with high tumor load. Blue points are significant positive correlations, red points are significant negative correlations and black points are bacteria in the sample uncorrelated with the tumor load. B, ROC curve of tumor load prediction. The input was the microbiome at T0 and the prediction was whether the final tumor load was below or above the median. C, ROC curve of tumor load prediction in CAC-induced samples of control-FMT and CAC-FMT mice together. The input was the microbiome at T15, the prediction was whether the final tumor load was below or above the median. D, Taxonomy tree of bacteria correlated with high tumor load in control-FMT and CAC-FMT mice. Blue points are significant positive correlations, red points are significant negative correlations, and black points are bacteria in the sample uncorrelated with the tumor load.

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